eCommerce didn't help their cause but employing people who didn't, on the majority, give a @*!# about what they were doing or selling never helped. Going into an old indie game store and chatting with the owner/employee about some upcoming games was well worth the extra couple of quid than buying online. But going into an overpriced, poorly staffed/trained shop with no interest in gaming isn't going to get you very far!
And the fact they had a ridiculously number of shops within walking distance of each other, I'm sure at one point there were 2 Game and 1 or 2 Gamestation shops in Manchester city centre.